Berberine

Short Description:

CAS No.:633-65-8
Packaging:25kg/Bag
Min.Order Quantity: 1000kgs

What is Berberine HCL Powder

Berberine HCL powder, short for Berberine Hydrochloride powder, is a high-purity natural quaternary isoquinoline alkaloid derived from traditional medicinal plants including Coptis chinensis, Phellodendron amurense, and Berberis vulgaris.  Appearing as fine bright yellow crystalline powder with slight bitterness and excellent water solubility, berberine hcl is of 97%–99% HPLC purity for global nutraceutical, pharmaceutical, and functional food applications.With the growing consumer demand for natural, science-backed healthy ingredients that support anti-inflammation, metabolic, cardiovascular, and gastrointestinal health, berberine hcl has become one popular natural functional ingredients in the global nutritional supplement, pharmaceutical, food, and cosmetic industries.


Product Detail

Product Tags

Specification

ITEM
SPECIFICATION
Assay  97%, 98%
Appearance Yellow crystal powder
Taste Characteristic
Extraction Solvent Ethanol & Water
Excipient None
Particle Size 100%Through 80 mesh
Loss on Drying ≤12.0%
Ash content ≤0.2%
Total Heavy Metals ≤20ppm
Pb ≤1ppm
As ≤2ppm
Residual Solvents Ethanol ≤3000ppm
Total Plate Count ≤1000cfu/g
herbal ingredients supplier

Berberine Powder Benefits

Metabolic Health & Blood Sugar Reduction

With the ability to help maintain healthy blood sugar levels, and improve insulin sensitivity, berberine powder has got widely recognized in the global daily and nutritional supplements industry. In addition, by activatin AMPK, berberine powder enhances glucose uptake by muscle cells, inhabits glucose production in the liver, and regulates the activity of enzymes involved in glucose metabolism, such as dipeptidyl peptidase-4 (DPP-4)—increasing GLP-1 levels by 40-50% to enhance the incretin effect. As the scientifical research showed, a daily dosage of 500mg berberine can reduce fasting blood sugar by 1.5-2.0mmol/L and glycated hemoglobin (HbA1c) by 0.8-1.2% in individuals with elevated blood sugar levels. Moreover, berberine supports weight management as well via promoting fatty acid oxidation and inhibiting fat cell growth, particularly targeting abdominal fat when combined with a healthy lifestyle.

Cardiovascular Health Support

Throuh regulating lipid metabolism and maintaining healthy cholestrol levels, berberine performs well in supporting cardiovascular health. Berberine lowers LDL (“bad” cholesterol) and triglyceride levels while increasing HDL (“good” cholesterol), reducing the risk of plaque buildup in blood vessels. Additionally, berberine exerts mild hypotensive effects, helping to maintain healthy blood pressure levels, and supports heart function by reducing inflammation in heart tissues and regulating heart rhythm.

Gastrointestinal & Gut Health Support

Bererine has shown significantly effect in antimicrobial activity against harmful gut bacteria (e.g., H. pylori), fungi, parasites, and viruses—consistent with its broad antimicrobial spectrum that includes gram-positive bacteria, gram-negative bacteria, various influenza viruses, and fungi. Meanhile, berberine can support the growth of beneficial gut microbiota, increasing the proportion of beneficial bacteria by 20-30% and promoting short-chain fatty acid production.

Antimicrobial & Anti-Inflammatory Effects

Bererine's function is not limited to gut health, it is also effective against a range of pathogens, including bacteria (e.g., Staphylococcus aureus, E. coli), fungi (e.g., Candida albicans), and viruses. Its anti-inflammatory activity is mediated by inhibiting NF-κB and other pro-inflammatory pathways, reducing chronic low-grade inflammation linked to metabolic disorders, joint discomfort, and skin aging.

Berberine Powder Application

Healthy Food & Beverage

In the healthy food processing industry, like protein bars and healthy snacks, berberine powder is added to enhance nutritional values. As for functional beverage processing industry, berberin powder is usually added into energy drinks, juice blends, and herbal teas to add metabolic and antioxidant benefits without overpowering flavor.

Daily & Nutritional Supplements

For those who manufacture daily and nutritional supplements targeting metabolic health, blood sugar support, cardiovascular health, and gut health, berberine powder is a necessary raw healthy ingredient. Most common forms include capsules, tablets, dissolvable powder sticks, and liquid shots—mirroring the tablet formulation (0.1g per tablet) commonly used in over-the-counter berberine products. Additionally, berberine powde is blended with other functional ingredients to enhance efficacy, such as milk thisle extract powder and tumeric extract powder.

In conclusion, berberine powder is one versatile and high-value natural ingredients with proven benefits for metabolic health, cardiovascular support, gut health, and antimicrobial protection. Besides, with the advanced extraction and processing technologies, the production capacity of berberine powder is more efficient, and sustainable. The bioactivity is higher as well, creating new opportunities for global healthy food manufacturers, nutritional and dietary nutritional supplements manufacturers to launch innovative and high-added value end products with lower production cost.

If you you are wondering where to buy factory price bulk pure berberine powder for your formulations and products, Tianjiachem, as one healthy food and nutritional supplements solutions supplier, will always provide you not just premium products with ISO22000, ISO9001, FDA, Kosher, HALAL certificates, but also solutions to help drive your business forward in the global market. Contact us today to discuss how we can collaborate and meet your specific needs.

1.More than 10 years experience with ISO certified,
2.Factory of flavor and sweetener blending,Tianjia Own Brands,
3.Research on the Market Knowledge & trend follow up,
4.Timely Deliver & Stock Promotion on hot demanding products,
5.Reliable & Strictly follow the contract responsibility & after sales service,
6. Professional on International Logistic Service, Legalization documents & Third Party Inspection process.


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